Evaluation of TSH And T4 Levels in Idiopathic Sudden Sensorineural Hearing Loss Patients

Objectives: to research on TSH, T4 levels and audiologic values of unilateral ISSNHL patients. Methods: The files of patients who treated with sudden sensorineural hearing loss diagnosis were retrospectively reviewed. Hematologic and biochemical parameters, vitamin B-12, free T4 (tetraiodothyronine), TSH (thyroid stimulating hormone), the initial and last audiologic report after treatment were recorded. Results: The study group consist of 60 patients (32 patients responder, 28 patient nonresponder) and the control group had 30 healthy persons. There was no significant difference in TSH and free T4 between the responder group and the control group. Serum free T4 was significantly lower in the nonresponder group comparing to the control group. There was no significant difference in TSH and T4 levels between subgroups of sudden hearing loss. Conclusion: Small variations in T4 levels can be a risk factor for ISSNHL even if the patient has euthyroidism and these changes can be either acute or chronic.